DRUSE

For those interested in ageing intervention studies, there is an article on the AGE journal which describes the development of a testing program for candidate interventions in mice. This was written by Nancy Nadon and colleagues. Below is the abstract:

“The field of biogerontology has made great strides towards understanding the biological processes underlying aging, and the time is ripe to look towards applying this knowledge to the pursuit of aging interventions. Identification of safe, inexpensive, and non-invasive interventions that slow the aging process and promote healthy aging could have a significant impact on quality of life and health care expenditures for the aged. While there is a plethora of supplements and interventions on the market that purport to slow aging, the evidence to validate such claims is generally lacking. Here we describe the development of an aging interventions testing program funded by the National Institute on Aging (NIA) to test candidate interventions in a model system. The development of this program highlights the challenges of long-term intervention studies and provides approaches to cope with the stringent requirements of a multi-site testing program.”

Fig. 1 Variation in median survival of C57BL/6 mice. Median lifespan of control, untreated male C57BL/6 mice from published studies is presented (see references).

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