DRUSE

We are still struggling up to this moment in purifying the molecule that we are interested in – DmWRNexo. It appears to behave in some “mysterious” ways. The peaks that come out after chromatography seems to vary. Last Friday, we got three peaks (three fractions). Under the electron microscope, I saw this morning how the individual particles from the first fraction look like. Quite nice, they remind me of tiny doughnuts (with a hole in the middle). But there weren’t enough of them in a single field of view, so we did not take a photo. Tomorrow, we shall see. We have a new sample today (completed at 1700), but the chromatography profile was so different, it had only one peak! In the end, Ivan and I exclaimed, “What is going on? We don’t know!”