Category Archives: homologous recombination
ATR and H2AX
Last month (December 2008) in the Journal of Biological Chemistry, Rebecca Chanoux and colleagues reported the results of their studies on ATR and H2AX. They wrote: “If ATR prevents the collapse of stalled replication forks into DSBs, and H2AX facilitates … Continue reading
human exonuclease 1 and BLM helicase
In a recent paper by Amitabh Nimonkar and colleagues, it was established that human BLM helicase, a member of the RecQ family, stimulates human exonuclease 1 (hExo1), a 5′ – 3′ double-stranded DNA exonuclease … “Stimulation of DNA resection by … Continue reading
WRN mini-review
In a recent issue of DNA Repair [7 (2008) 1776–1786], Julia Sidorova reviews the role of WRN in preserving DNA integrity during replication and propose that WRN can function in coordinating replication fork progression with replication stress-induced fork remodeling. She … Continue reading
