Tag Archives: BLM
RecQ and recombination-based DNA repair
Dharmendra Kumar Singh and colleagues wrote an article in the Biogerontology journal presenting the various roles of human RecQ helicases in recombination-based DNA repair. The physiological consequences of RecQ defects in the development of cancer and premature aging were also … Continue reading
Filed under ageing, aging, biogerontology, RecQ
BLM helicase as a mousetrap
Robert Brosh, Jr. wrote an article on Nature about the BLM helicase [Nature 456, 453-454 (27 November 2008) | doi:10.1038/456453a; Published online 26 November 2008]. His introductory paragraph goes: “Bloom’s syndrome, which is characterized by severe growth retardation, immunodeficiency, anaemia, … Continue reading
Filed under Bloom's syndrome
human exonuclease 1 and BLM helicase
In a recent paper by Amitabh Nimonkar and colleagues, it was established that human BLM helicase, a member of the RecQ family, stimulates human exonuclease 1 (hExo1), a 5′ – 3′ double-stranded DNA exonuclease … “Stimulation of DNA resection by … Continue reading
Back from Heidelberg
I’m back from Heidelberg. My original plan was to blog during the entire symposium, but that did not materialize. I will write more about the three days soon. In the meantime, here is an interesting paper on Sgs1 and BLM … Continue reading
