Tag Archives: cancer

the common biology of cancer and ageing

Let us revisit the review paper by Toren Finkel and colleagues in which they discussed “key observations that has led to a complex but growing convergence between our understanding of the biology of ageing and the mechanisms that underlie cancer” … Continue reading

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Filed under ageing, aging, cancer, stem cells

cancer and ageing

There’s a special issue in the journal Mechanisms of Ageing and Development devoted to cancer and ageing. Below is the intro from the editors: “An understanding of the relationship between aging and cancer is of more than mere academic interest. … Continue reading

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Filed under ageing, aging, cancer

DSB DNA repair genotype predictive of later mortality

A number of pathways operate to repair DNA damage: nucleotide excision repair (NER), base excision repair (BER), double-strand breaks (DSB), and mismatch repair (MMR). In a study by David Neasham and colleagues, single nucleotide polymorphisms in 16 DNA repair genes … Continue reading

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Filed under cancer, DNA, DNA damage, DNA repair, double strand break, dying, gene, genetics, life sciences, mortality, research, science