Tag Archives: Drosophila melanogaster
amino acid imbalance explains lifespan extension by dietary restriction in fruitflies
A study by Richard Grandison, Matthew Piper, and Linda Partridge (Nature advance online publication 2 December 2009 | doi:10.1038/nature08619) has identified the nutrients producing the responses of lifespan and fecundity to dietary restriction (DR) in the fruitfly Drosophila. “Adding essential … Continue reading
Filed under amino acids, dietary restriction, DR, drosophila, fecundity, fertility, fly, fruitfly, lifespan, lifespan extension
flies fed an “anti-Atkins” low protein diet live longer
Researchers at the Buck Institute are studying the regulation of mitochondrial genes in the fruitfly Drosophila melanogaster in relation to ageing and lifespan. They are trying to understand how mitochondrial function relates to diet and energy metabolism, specifically the molecular … Continue reading
Filed under 4EBP, ageing, aging, anti-ageing, anti-aging, Atkins diet, diet, dietary restriction, DR, drosophila, fly, fruitfly, lifespan, longevity, low-protein diet, mitochondrial DNA, rapamycin, target of rapamycin, TOR
perdurance
In 1971, Antonio Garcia-Bellido and John Merriam introduced the concept of perdurance to describe the persistence of a gene’s product after the removal of a gene from a cell. For example, if by mitotic exchange a m/m cell is made … Continue reading
Filed under drosophila, genetics, mitotic exchange, perdurance
telomere loss produces genomic instability
Simon Titen and Kent Golic studied telomere loss by breakage of an induced dicentric chromosome in the fruitfly Drosophila melanogaster [Genetics 2008 Dec;180(4):1821-32; Epub 2008 Oct 9]. They found that one outcome of this is cell death through Chk2 and … Continue reading
