Tag Archives: genetics

online publication

The GENETICS journal, published by the Genetics Society of America, has issued a statement which I think will soon be followed by many other similar publications. There will not be a print version of the journal anymore. Instead, it will … Continue reading

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Filed under electronic, genetics, html, journal, pdf, publication, publishing

re-write the textbooks: transcription is bidirectional

Genes that contain instructions for making proteins make up less than 2% of the human genome. Yet, for unknown reasons, most of our genome is transcribed into RNA. The same is true for many other organisms that are easier to … Continue reading

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Filed under transcription

oxidatively damaged DNA in the germ line

Alberto Velando and colleagues wrote a paper entitled “Avoiding bad genes: oxidatively damaged DNA in germ line and mate choice.” Below is the abstract: August Weismann proposed that genetic changes in somatic cells cannot pass to germ cells and hence … Continue reading

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Filed under ageing, aging

BLAP75/Rmi1

Liudmila Chelysheva and colleagues studied BLAP75/Rmi1 in relation to BLM/Sgs1 and TopoIIIα/Top3. Their paper appeared on the December 2008 issue of PLoS Genetics journal. Below is the summary: “Recombination is a process by which cells can repair DNA damage. Such … Continue reading

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Filed under DNA damage, DNA repair, genetics, genome stability

perdurance

In 1971, Antonio Garcia-Bellido and John Merriam introduced the concept of perdurance to describe the persistence of a gene’s product after the removal of a gene from a cell. For example, if by mitotic exchange a m/m cell is made … Continue reading

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Filed under drosophila, genetics, mitotic exchange, perdurance

maternally inherited piRNAs

In hybrid dysgenesis (Drosophila melanogaster), the progeny of intercrosses between wild males and laboratory-strain females are sterile because of defects in gamete formation. This has something to do with the mobilization of transposons. Depending on the parent of transposon origin, … Continue reading

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Filed under females