Tag Archives: lifespan

life expectancy in the UK

A recent update from the UK Statistics Authority indicated that life expectancy in England has continued to increase for both males and females, reaching 78.0 and 82.1 years respectively in 2007-09. In addition, premature mortality rates from circulatory diseases for … Continue reading

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Filed under ageing, life expectancy, lifespan

review on lifespan extension

There is a new review on Science (by Luigi Fontana, Linda Partridge, and Valter Longo) discussing recent findings in ageing research supporting the idea that lifespan can be extended by dietary and genetic alterations. Many studies have shown that reducing … Continue reading

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Filed under lifespan, lifespan extension, reviews

amino acid imbalance explains lifespan extension by dietary restriction in fruitflies

A study by Richard Grandison, Matthew Piper, and Linda Partridge (Nature advance online publication 2 December 2009 | doi:10.1038/nature08619) has identified the nutrients producing the responses of lifespan and fecundity to dietary restriction (DR) in the fruitfly Drosophila. “Adding essential … Continue reading

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Filed under amino acids, dietary restriction, DR, drosophila, fecundity, fertility, fly, fruitfly, lifespan, lifespan extension

flies fed an “anti-Atkins” low protein diet live longer

Researchers at the Buck Institute are studying the regulation of mitochondrial genes in the fruitfly Drosophila melanogaster in relation to ageing and lifespan. They are trying to understand how mitochondrial function relates to diet and energy metabolism, specifically the molecular … Continue reading

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Filed under 4EBP, ageing, aging, anti-ageing, anti-aging, Atkins diet, diet, dietary restriction, DR, drosophila, fly, fruitfly, lifespan, longevity, low-protein diet, mitochondrial DNA, rapamycin, target of rapamycin, TOR

rapamycin increases lifespan in mice

Lynne Cox wrote an article on the BSRA News Section about the recent Nature paper by David Harrison and colleagues: Rapamycin fed late in life extends lifespan in genetically heterogeneous mice; Nature 460, 392-395 (16 July 2009); doi:10.1038/nature08221; Published online … Continue reading

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Filed under ageing, aging, anti-ageing, anti-aging, longevity, mice, rapamycin

synaptic proteins, IGF signaling, and lifespan

In a paper by QueeLim Ch’ng and colleagues, a genetic analysis of presynaptic structure in the worm Caenorhabditis elegans was described after measuring in vivo changes in the distribution of fluorescently tagged presynaptic proteins. Because changes in the abundance of … Continue reading

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Filed under c.elegans, IGF, lifespan