Tag Archives: mitochondrial DNA
flies fed an “anti-Atkins” low protein diet live longer
Researchers at the Buck Institute are studying the regulation of mitochondrial genes in the fruitfly Drosophila melanogaster in relation to ageing and lifespan. They are trying to understand how mitochondrial function relates to diet and energy metabolism, specifically the molecular … Continue reading
Filed under 4EBP, ageing, aging, anti-ageing, anti-aging, Atkins diet, diet, dietary restriction, DR, drosophila, fly, fruitfly, lifespan, longevity, low-protein diet, mitochondrial DNA, rapamycin, target of rapamycin, TOR
somatic mtDNA mutations
A paper by Alexandra Kukat and Aleksandra Trifunovic demonstrates that somatic mtDNA mutations have the capacity to cause a variety of aging phenotypes in mammals. However, the relative importance of somatic mtDNA mutations in mammalian aging remains unclear, as the … Continue reading
Filed under ageing, aging, senescence
mitochondrial DNA subunits
Rajindar Sohal and colleagues recently made a study comparing the expression of mitochondrial DNA encoded subunits of cytochrome c oxidase (CcO) in Drosophila melanogaster. They compared mitochondrial proteins from 15-, 25-, 35-, 47- and 60-day-old flies. Subunits I, II and … Continue reading
Filed under ageing, aging, biology, drosophila, genetics, mitochondrial DNA, molecular biology
