Tag Archives: science
when it doesn’t work
I think most people who work in an experimental research lab recognise that not all experiments yield good results. And so today, I found out that the RTS 100 synthesis I did yesterday was of no good at all. What … Continue reading
Filed under ageing, experiments
moments of not knowing
We are still struggling up to this moment in purifying the molecule that we are interested in – DmWRNexo. It appears to behave in some “mysterious” ways. The peaks that come out after chromatography seems to vary. Last Friday, we … Continue reading
Filed under experiments
re-write the textbooks: transcription is bidirectional
Genes that contain instructions for making proteins make up less than 2% of the human genome. Yet, for unknown reasons, most of our genome is transcribed into RNA. The same is true for many other organisms that are easier to … Continue reading
Filed under transcription
oxidatively damaged DNA in the germ line
Alberto Velando and colleagues wrote a paper entitled “Avoiding bad genes: oxidatively damaged DNA in germ line and mate choice.” Below is the abstract: August Weismann proposed that genetic changes in somatic cells cannot pass to germ cells and hence … Continue reading
BLAP75/Rmi1
Liudmila Chelysheva and colleagues studied BLAP75/Rmi1 in relation to BLM/Sgs1 and TopoIIIα/Top3. Their paper appeared on the December 2008 issue of PLoS Genetics journal. Below is the summary: “Recombination is a process by which cells can repair DNA damage. Such … Continue reading
Filed under DNA damage, DNA repair, genetics, genome stability
the scientist and the identifier
“Initiatives such as OpenID (http://openid.net/) and ResearcherID (http://www.researcherid.com/), if they catch on in the scientific community, promise to provide us with unique identifiers.” Philip Bourne and J. Lynn Fink wrote on the journal PLoS Computational Biology. Bourne PE, Fink JL … Continue reading
maternally inherited piRNAs
In hybrid dysgenesis (Drosophila melanogaster), the progeny of intercrosses between wild males and laboratory-strain females are sterile because of defects in gamete formation. This has something to do with the mobilization of transposons. Depending on the parent of transposon origin, … Continue reading
Filed under females
