Tag Archives: senescence
rDNA theory of aging
The ribosomes are the most abundant protein complexes in the cell. They are synthesised from ribosomal DNA (rDNA) genes within nucleoli. In most eukaryotic cells, rDNA exists in tandem arrays, which are repeating units of similar sequences. Oftentimes the rDNA … Continue reading
Filed under ageing
somatic mtDNA mutations
A paper by Alexandra Kukat and Aleksandra Trifunovic demonstrates that somatic mtDNA mutations have the capacity to cause a variety of aging phenotypes in mammals. However, the relative importance of somatic mtDNA mutations in mammalian aging remains unclear, as the … Continue reading
Filed under ageing, aging, senescence
senescence and disease
There’s a review paper that came out recently on Mechanisms of Ageing and Development journal ( Volume 129, Issue 12, December 2008, Pages 693-699). It is entitled “Does senescence give rise to disease?” by Bruce Carnes and colleagues. Here’s a … Continue reading
Filed under ageing, aging, anti-ageing, anti-aging, senescence
