Tag Archives: structural biology and ageing

toolbox for 3-D reconstruction

If you do molecular reconstruction by electron microscopy, this might be useful for you. Neil Voss and colleagues developed a “toolbox” of ab initio reconstruction techniques for 3-D reconstruction: ” … an easily managed and tightly controlled work-flow that adheres … Continue reading

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Filed under electron microscopy, structural biology, structural biology and ageing

structural conservation in TOR pathway

In the Journal of Molecular Biology, there is now a crystal structure of yeast Gse1p, or Gse1p/Ego3p/Slm4p/Nir1p, a component of the EGO-GSE protein complex in endosomal and vacuolar membranes of Saccharomyces cerevisiae. Deletion of genes encoding the proteins that make … Continue reading

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Filed under crystal structure, crystallography, structural biology, structural biology and ageing, target of rapamycin, TOR

structural biology and ageing

Currently, I’ve been reading a set of journal articles about protein folding and protein-nucleic acid interactions on: Current Opinion in Structural Biology (Volume 20, Issue 1, February 2010). The introduction was written by Laura Itzhaki and Peter Wolynes: “Human beings … Continue reading

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Filed under ageing, structural biology, structural biology and ageing